JAM3 anticorps (AA 32-241)
Aperçu rapide pour JAM3 anticorps (AA 32-241) (ABIN7539787)
Antigène
Voir toutes JAM3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 32-241
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Fonction
- JAM3 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human JAM3 (AA: 32-241) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- JAM3 (Junctional Adhesion Molecule 3 (JAM3))
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Autre désignation
- JAM3
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Sujet
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 35 kDa
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UniProt
- Q9BX67
Antigène
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